High-Flow Nasal Cannula (HFNC)

High-Flow Nasal Cannula (HFNC)

Overview

High-Flow Nasal Cannula is a non-invasive respiratory support system that delivers heated, humidified oxygen at flows higher than traditional nasal cannula, providing improved oxygenation and ventilation support in pediatric patients.

Key Mechanisms of Action

  • Physiological Effects:
    • Washout of nasopharyngeal dead space
    • Reduction in upper airway resistance
    • Provision of positive end-expiratory pressure (PEEP)
    • Improved mucociliary clearance
    • Decreased work of breathing
  • Flow Rates:
    • Neonates: 4-8 L/min
    • Infants: 8-12 L/min
    • Toddlers: 12-20 L/min
    • School-age: 20-30 L/min
    • Adolescents: Up to 60 L/min

System Setup & Components

Essential Components

  • Flow Generator
    • Air/oxygen blender
    • Flow meter
    • Pressure monitoring system
    • Safety alarms
  • Humidification System
    • Heated humidifier
    • Temperature control
    • Water chamber
    • Heated wire circuits
  • Patient Interface
    • Age-appropriate nasal cannula
    • Securing mechanism
    • Skin protection

Size Selection

  • Cannula Sizing
    • Neonatal: Prong outer diameter ≤ 2.4 mm
    • Infant: 2.4-3.0 mm
    • Pediatric: 3.0-4.0 mm
    • Adult small: 4.0-5.0 mm
  • Proper Fit Guidelines
    • Prongs should occupy ≤50% of nares
    • No pressure on septum
    • Allow for patient movement
    • Check for air leak around prongs

Clinical Applications

Primary Indications

  • Respiratory Conditions
    • Bronchiolitis
    • Pneumonia
    • Asthma
    • Post-extubation support
    • Acute hypoxemic respiratory failure
  • Other Applications
    • Apnea of prematurity
    • Cardiac conditions with respiratory compromise
    • Pre-oxygenation before procedures
    • Sleep-disordered breathing

Initial Settings

  • Flow Rate Initiation
    • Start at age-appropriate flow
    • Titrate based on work of breathing
    • Monitor patient comfort
    • Assess response within 1-2 hours
  • FiO2 Management
    • Start at FiO2 needed for SpO2 target
    • Wean as tolerated
    • Monitor oxygen requirements

Contraindications

  • Absolute
    • Nasal obstruction
    • Base of skull fractures
    • Severe coagulopathy
  • Relative
    • Severe respiratory acidosis
    • Hemodynamic instability
    • Altered mental status
    • Excessive secretions

Monitoring & Troubleshooting

Patient Assessment

  • Clinical Monitoring
    • Respiratory rate and effort
    • SpO2 and heart rate trends
    • Work of breathing
    • Mental status
    • Comfort level
  • System Checks
    • Water level
    • Circuit temperature
    • Cannula position
    • Circuit condensation

Common Problems & Solutions

  • Inadequate Response
    • Verify flow rate adequacy
    • Check for air leaks
    • Assess cannula position
    • Consider escalation of care
  • Equipment Issues
    • Circuit temperature alarms
    • Water depletion
    • Cannula displacement
    • Flow interruption

Weaning Protocol

  • Readiness Assessment
    • Clinical improvement
    • Stable oxygen requirements
    • Adequate work of breathing
    • Stable vital signs
  • Weaning Steps
    • Reduce FiO2 first
    • Gradually decrease flow
    • Monitor tolerance
    • Have rescue plan ready


Further Reading
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