End-Tidal CO₂ (ETCO₂) Monitoring

Overview

End-tidal CO₂ monitoring, or capnography, is a non-invasive method for measuring expired CO₂ levels, providing crucial information about ventilation, perfusion, and metabolism in pediatric patients.

Key Points

  • Continuous real-time monitoring of respiratory status
  • Early detection of respiratory compromise
  • Normal ETCO₂ range: 35-45 mmHg
  • Provides both numeric values and waveform analysis
  • Essential for procedural sedation monitoring

Physiological Principles

CO₂ Transport

  • Cellular production of CO₂
  • Transport in blood (dissolved, bicarbonate, bound to proteins)
  • Pulmonary circulation and gas exchange
  • Alveolar ventilation
  • V/Q matching principles

Respiratory Cycle Components

  • Phase I: Dead space ventilation
  • Phase II: Mixed dead space and alveolar gas
  • Phase III: Alveolar plateau
  • Phase IV: Beginning of inspiration

Monitoring Methods

Technology Types

  • Mainstream capnography
    • Sensor directly in airway
    • Faster response time
    • Better for neonates/small children
  • Sidestream capnography
    • Sample diverted to sensor
    • More versatile applications
    • Requires adequate sample flow

Equipment Setup

  1. Calibration requirements
  2. Sampling line connections
  3. Filter maintenance
  4. Zero baseline establishment
  5. Alarm setting configuration

Clinical Applications

Primary Indications

  • Mechanical ventilation monitoring
  • Procedural sedation
  • Cardiopulmonary resuscitation
  • Endotracheal tube placement verification
  • Transport monitoring
  • Respiratory disease management

Specific Clinical Scenarios

  • Operating room monitoring
    • Airway assessment
    • Ventilation adequacy
    • Metabolic status
  • Critical care
    • Ventilator weaning
    • Respiratory deterioration
    • CPR quality assessment

Waveform Analysis & Interpretation

Normal Capnogram Components

  • Baseline (0 mmHg)
  • Exponential rise
  • Alveolar plateau
  • Inspiratory descent

Abnormal Patterns

  • Bronchospasm
    • Shark fin appearance
    • Prolonged Phase III
  • Hyperventilation
    • Decreased ETCO₂
    • Increased respiratory rate
  • Hypoventilation
    • Elevated ETCO₂
    • Decreased respiratory rate
  • Rebreathing
    • Elevated baseline
    • Incomplete return to zero

Pediatric-Specific Considerations

Age-Related Factors

  • Neonatal considerations
    • Higher respiratory rates
    • Smaller tidal volumes
    • Equipment size selection
  • Infants and toddlers
    • Sampling method selection
    • Movement artifacts
    • Normal value variations

Technical Adaptations

  • Equipment modifications
  • Sampling flow rates
  • Dead space considerations
  • Interface selection

Monitoring Challenges

  • Patient cooperation
  • Mask fit issues
  • Oral vs nasal breathing
  • Activity level impact


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