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Blood Gas Analyzer in Pediatrics

Blood Gas Analyzer in Pediatrics

Overview

Blood gas analyzers are critical diagnostic instruments that measure various parameters in blood samples, providing vital information about a patient's respiratory, metabolic, and acid-base status. In pediatrics, these devices are specially calibrated for smaller sample volumes and rapid analysis.

Key Features

  • Sample Volume Requirements:
    • Microsampling capability (35-95 μL)
    • Neonatal-specific cartridges
    • Capillary sample analysis
  • Analysis Time: 35-120 seconds
  • Result Storage: Up to 1000 patient results
  • Quality Control: Automated calibration systems

Parameters and Interpretation

Primary Measurements

  • Blood Gases:
    • pH (Normal range: 7.35-7.45)
    • PaO2 (80-100 mmHg)
    • PaCO2 (35-45 mmHg)
    • HCO3- (22-26 mEq/L)
  • Electrolytes:
    • Sodium (Na+)
    • Potassium (K+)
    • Ionized Calcium (iCa2+)
    • Chloride (Cl-)
  • Metabolites:
    • Glucose
    • Lactate
    • Blood Urea Nitrogen
  • Co-Oximetry:
    • Total Hemoglobin (tHb)
    • Oxygen Saturation (SO2)
    • Carboxyhemoglobin (COHb)
    • Methemoglobin (MetHb)

Derived Parameters

  • Base Excess (BE)
  • Anion Gap
  • P50
  • Oxygen Content (CaO2)

Clinical Applications and Indications

Primary Clinical Uses

  • Respiratory Management:
    • Ventilator adjustments
    • Oxygen therapy monitoring
    • Respiratory distress assessment
    • Asthma severity evaluation
  • Critical Care:
    • Shock assessment
    • Cardiac function monitoring
    • Metabolic disorder evaluation
    • Sepsis monitoring
  • Specialized Units:
    • NICU monitoring
    • PICU management
    • Post-operative care
    • Emergency department triage

Diagnostic Applications

  • Acid-base disorders
  • Respiratory failure
  • Metabolic diseases
  • Electrolyte imbalances
  • Toxicological emergencies

Sampling Techniques and Procedures

Sample Collection Methods

  • Arterial Sampling:
    • Radial artery technique
    • Umbilical arterial line
    • Arterial catheter sampling
  • Capillary Sampling:
    • Heel stick procedure
    • Finger prick technique
    • Earlobe sampling
  • Venous Sampling:
    • Central line collection
    • Peripheral venous draw

Sample Handling

  • Temperature control
  • Air bubble removal
  • Time to analysis limits
  • Sample mixing requirements

Troubleshooting and Quality Control

Common Issues

  • Pre-analytical Errors:
    • Air bubbles in sample
    • Clotted specimens
    • Inadequate sample volume
    • Delayed analysis
  • Analytical Errors:
    • Calibration failures
    • Sensor malfunctions
    • Temperature compensation errors
  • Quality Control:
    • Daily QC procedures
    • Calibration verification
    • Proficiency testing

Maintenance Schedule

  • Daily: Sensor check and calibration
  • Weekly: Deep cleaning procedures
  • Monthly: Performance verification
  • Quarterly: Preventive maintenance
Further Reading


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